发明名称 ANTIBODIES DIRECTED TO THE DELETION MUTANTS OF EPIDERMAL GROWTH FACTOR RECEPTOR AND USES THEREOF.
摘要 The present invention relates to novel antibodies, particularly antibodies directed against deletion mutants of epidermal growth factor receptor and particularly to the type III deletion mutant, EGFRvIII. The invention also relates to human monoclonal antibodies directed against deletion mutants of epidermal growth factor receptor and particularly to EGFRvIII. Diagnostic and therapeutic formulations of such antibodies, and immunoconjugates thereof, are also provided.
申请公布号 MXPA05014152(A) 申请公布日期 2006.05.25
申请号 MX2005PA14152 申请日期 2004.06.25
申请人 ABGENIX, INC. 发明人 SU QUIAOJUAN JANE
分类号 C12N;A61K39/395;A61K47/48;C07K16/22;C07K16/28;C07K17/00;C12N5/06;G01N33/53 主分类号 C12N
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