CATHEPSIN H PROTEIN-DERIVED CD8+ CYTOTOXIC T-LYMPHOCYTE mHA EPITOPE PEPTIDE AND APPLICATION THEREOF

摘要

PROBLEM TO BE SOLVED: To provide a CD8+cytotoxic T-lymphocyte epitope peptide useful for treating hematogenous organ tumor or solid tumor left or relapsed after hematopoietic stem cell transplantation or for preventing such tumor.

SOLUTION: The peptide is a partial peptide of Cathepsin H protein, being a minor histocompatibility antigen(mHA) epitope peptide recognizable by CD8+cytotoxic T-lymphocyte through binding to a human leukocyte antigen(HLA).

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