发明名称 PROCEDURE FOR OBTAINING DAILY CREAM PREPARATION BASED ON THE COMBINATION OF BIOACTIVE COMPONENTS USED IN TREATMENT OF AGED SKIN
摘要 Procedure for obtaining daily cream preparation based on the combination of bioactive components used in treatment of aged skin is characterized by that aqueous phase (30,00 - 90,00 mass %), is heated at 40 - 85 °C, where hydrophile components are dissolved: propylenglycol (2,00 - 30,00 mass %), imidazolidinylurea (0,05 - 0,60 mass %), polysorbate 60 (0,05 - 5,00 mass %), is added during oily phase heated up to the temperature 45 - 85 °C with lipophylic components: sorbitan stearate and stearic acid (0,05 - 5,00 mass %), octylmethoxysicinamate (0,50 - 7,50 mass %) C12 - C15 of alkyl benzoate, (0,01 - 0,10 mass %) , 4-metylbenzylidene camphor (0,5 - 5,00 mass %), jojoba oil (0,50 - 0,60 mass %). When cooled with permanent mixing up to the temperature in range of 50 - 55 °C, the remaining ingredients are added: butyhydoxytoluene, (0,05 - 0,60 mass %) (0,01 - 0,60 mass %) phenoxyethanol-methyl-ethyl-ethyl-propyl-paraben (0,20 -5,00 mass %), vitamin E acetate, omega 6 polyunsaturated acids (0,35- 1,05 mass %), vitamin A palmitate (0,005 - 0,45 mass %), hydrolyzed collagen 0,2 - 1,50 mass %), hydrolyzed elastine (0,20 - 1,50 mass %), provitamin B5 (0,20 -5,00 mass %), and hyaluronic acid (0,01 - 0,05 mass %) and continue with mixing and cooling up to about 40 °C , and then add (0,10 - 0,50 mass %) of scented component and continue with mixing at the speed of 50 rpm, during 30 minutes, where a cream of homogenous appearance, fragrance having origin in the scented component is obtained, and its pH value range is within 4,5 - 8,0.
申请公布号 YU72502(A) 申请公布日期 2006.05.25
申请号 YU2002P000725 申请日期 2002.09.25
申请人 HEMOFARM KONCERN A.D. FARMACEUTSKO-HEMIJSKA INDUSTRIJA VRSAC 发明人 GOLIC, SPOMENKA;PAVKOV, RUZICA;PETROVIC, SLOBODAN
分类号 (IPC1-7):A61K7/48 主分类号 (IPC1-7):A61K7/48
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