The present invention provides compounds of the Formula I and II, wherein R1, R3, W, Z, X1, X2, Ar1, R8 and R9 are as defined herein, processes and intermediates for their preparation and their use for the treatment of p38 mediated disorders.
申请公布号
YU63703(A)
申请公布日期
2006.05.25
申请号
YU2003P000637
申请日期
2002.02.04
申请人
F. HOFFMANN-LA ROCHE AG.
发明人
CHEN, JIAN JEFFREY;DUNN, JAMES PATRICK;GOLDSTEIN, DAVID MICHAEL;STAHL, CHRISTOPH MARTIN