| 发明名称 |
IMIDES AS TNF-alpha INHIBITOR |
| 摘要 |
PROBLEM TO BE SOLVED: To provide a method for reducing TNF (tumor necrosis factor)-αlevel in mammals and obtain a compound and a composition that are useful in the method. SOLUTION: The imides are the inhibitory agents of tumor necrosis factorαand can be used to control cachexia, endotoxic shock, and retrovirus replication. COPYRIGHT: (C)2006,JPO&NCIPI
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| 申请公布号 |
JP2006131647(A) |
申请公布日期 |
2006.05.25 |
| 申请号 |
JP20060039629 |
申请日期 |
2006.02.16 |
| 申请人 |
CELGENE CORP;MULLER GEORGE W |
发明人 |
MULLER GEORGE W |
| 分类号 |
C07D209/66;C07D307/66;A61K31/16;A61K31/165;A61K31/215;A61K31/275;A61K31/33;A61K31/34;A61K31/341;A61K31/40;A61K31/403;A61K31/4035;A61K31/404;A61K31/405;A61K31/415;A61K31/4178;A61K31/4188;A61K31/435;A61K31/437;A61K31/44;A61K31/4412;A61K31/4427;A61K31/443;A61K31/4439;A61K31/4465;A61K31/45;A61K31/454;A61P31/12;A61P31/18;A61P35/00;A61P37/04;A61P43/00;C07C229/08;C07C229/20;C07C229/22;C07C229/34;C07C237/04;C07C255/50;C07D209/08;C07D209/18;C07D209/46;C07D209/48;C07D209/50;C07D209/76;C07D211/88;C07D213/55;C07D401/04;C07D401/06;C07D401/12;C07D403/06;C07D403/12;C07D405/12;C07D471/04;C07D487/04;C07D495/04 |
主分类号 |
C07D209/66 |
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