发明名称 |
NOVEL 1,3-DIHYDRO-2H-INDOL-2-ONE DERIVATIVES AND THEIR USE AS LIGANDS FOR V1B AND V1A ARGININE-VASOPRESSIN RECEPTOR |
摘要 |
The invention concerns compounds of formula (I) and their possible salts with mineral or organic acids, their solvates and/or hydrates, having affinity and selectivity for V1b receptor or for both V1b and V1a arginine-vasopressin receptors. The invention also concerns their preparation method, intermediate compounds of formula (II) used in their preparation, pharmaceutical compositions containing them for use in preparing medicines. |
申请公布号 |
YU52302(A) |
申请公布日期 |
2006.05.25 |
申请号 |
YU2002P000523 |
申请日期 |
2001.01.24 |
申请人 |
SANOFI-AVENTIS |
发明人 |
ROUX, RICHARD;SERRADEIL-LE, GAL CLAUDINE;TONNERRE, BERNARD;WAGNON, JEAN |
分类号 |
A61K;A61K31/404;A61K31/405;A61K31/496;A61K31/5377;A61P;A61P1/00;A61P1/18;A61P3/06;A61P3/08;A61P5/38;A61P5/50;A61P7/04;A61P9/00;A61P9/10;A61P9/12;A61P11/06;A61P13/02;A61P15/04;A61P15/12;A61P17/06;A61P25/00;A61P25/02;A61P25/06;A61P25/16;A61P25/18;A61P25/22;A61P25/24;A61P25/28;A61P27/12;A61P29/00;A61P35/00;A61P37/06;A61P37/08;A61P43/00;C07D;C07D207/12;C07D209/04;C07D209/34;C07D403/04;C07D403/14;C07D405/06;C07D405/14 |
主分类号 |
A61K |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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