发明名称 |
Identification and use of cofactor independent phosphoglycerate mutase as a drug target for pathogenic organisms and treatment of the same |
摘要 |
Present embodiments of the invention describe computational methods for performing a systematic, genome-wide search for novel drug targets in pathogenic organisms for example, the human filarial parasites. Cofactor independent phosphoglycerate mutase (iPGM) was identified by this search as a candidate target for identifying therapeutic agents for use in treating animal or plant subjects infected with parasitic nematodes, microbial pathogens including microsporidia, fungi etc. A consensus amino acid or nucleotide sequence that characterizes iPGM is further provided.
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申请公布号 |
US2006111848(A1) |
申请公布日期 |
2006.05.25 |
申请号 |
US20050316521 |
申请日期 |
2005.12.22 |
申请人 |
NEW ENGLAND BIOLABS, INC. |
发明人 |
CARLOW CLOTILDE;ZHANG YINHUA;FOSTER JEREMY;KUMAR SANJAY |
分类号 |
G06F19/00;A61K;G01N33/44 |
主分类号 |
G06F19/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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