发明名称 |
USE OF 13C-NMR TO DETECT BINDING |
摘要 |
<p>Methods of detecting binding of a putative ligand to a 13C-enriched target molecule, methods of screening for compounds which bind to a 13C-enriched target molecule, methods for calculating the dissociation constant of a ligand compound which binds to a 13C-enriched target molecule, and methods employed in the determination of the specific amino acids in a 13C-enriched target molecule affected by the binding of a ligand, as well as compounds identified by these screening methods, are provided herewith.</p> |
申请公布号 |
EP1169648(B1) |
申请公布日期 |
2006.05.24 |
申请号 |
EP20000918228 |
申请日期 |
2000.03.21 |
申请人 |
ABBOTT LABORATORIES |
发明人 |
FESIK, STEPHEN, W.;HAJDUK, PHILIP, J. |
分类号 |
G01N24/12;G01N33/68;B08B9/04;C07B61/00;C07K1/13;E21B37/04;G01N33/483;G01N33/50;G01N33/53;G01N33/542;G01N33/566;G01N33/58;G01N33/94;G01R33/46;G01R33/465 |
主分类号 |
G01N24/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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