| 摘要 |
A process comprising reacting an aliphatic carboxylic ester compound with acetonitrile in the presence of a metal alkoxide to yield a metal salt of a beta-ketonitrile compound, subsequently transferring the salt to an aqueous medium, and neutralizing the solution to obtain the beta-ketonitrile compound in a free state, wherein a water-immisible organic solvent and water are added to the reaction mixture containing the beta-ketonitrile compound metal salt yielded to transfer the metal salt to the water, the resultant aqueous solution of the beta-ketonitrile compound metal salt is separated from the organic solvent by phase separation or another technique and then neutralized, and the resultant free beta-ketonitrile compound is taken out by extraction with an organic solvent.
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