| 摘要 |
A compound represented by the formula [I] : [I] (wherein ring A and ring B each represents an optionally substituted benzene ring; ring C represents an optionally further substituted aromatic ring; R1 represents a lower alkyl optionally substituted by optionally substituted hydroxy; X1a represents a bond or optionally substituted lower alkylene; X1b represents a bond or optionally substituted lower alkylene; X2 represents a bond, -O-, or -S-; X3 represents a bond or an optionally substituted divalent hydrocarbon group; and Y represents optionally esterified or amidated carboxy) or a salt of the compound. The compound of the formula [I] is safer and has more potent lipid-lowering activity such as squalene synthase inhibitory activity (cholesterol- lowering activity) and triglyceride-lowering activity. The compound is useful as a medicine for, e.g., the prevention of and treatments for hyperlipemia.
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