METHODS OF TREATING TYPE I DIABETES BY BLOCKING VEGF-MEDIATED ACTIVITY

摘要

Methods of treating diabetes in mammals, particularly humans, by blocking or inhibiting VEGF-mediated activity. A preferred inhibitor of VEGF-mediated activity is a VEGF antagonist such as the VEGF fusion protein trap of SEQ ID NO: 2 capable of binding and blocking VEGF. The method of the invention may be combined with other therapies, such as with insulin therapy.