摘要 |
PROBLEM TO BE SOLVED: To provide a technique for actualizing transfer of a nucleic acid substance to a cell, with which the nucleic acid substance is mixed with a minute needle-like substance and the cell and the mixture is provided with sliding friction by applying fixed force to the mixture so that the minute needle-like substance having adsorbed the nucleic acid substance is penetrated into the cell. SOLUTION: The surface of a culture substrate of a flat plate is coated with a mixture of the nucleic acid substance, the minute needle-like substance and the cell and then scrubbed while applying fixed force in a prescribed direction to the surface of the culture substrate of the flat plate to give the sufficient transfer efficiency of the nucleic acid substance. COPYRIGHT: (C)2006,JPO&NCIPI
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