发明名称 |
MODULATORS OF RETINOL-RETINOL BINDING PROTEIN (RBP)-TRANSTHYRETIN (TTR) COMPLEX FORMATION |
摘要 |
Described herein are methods and compositions for the detection of transthyretin (TTR), retinol binding protein (RBP) and retinol complex formation. The methods and compositions described herein also provide for th e screening of modulators of retinol-RBP-TTR complex formation. Furthermore, t he methods and compositions provide for therapeutic agents for the treatment and/or prevention of age-~related macular degeneration and/or dystrophies.</ SDOAB>
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申请公布号 |
CA2584396(A1) |
申请公布日期 |
2006.05.18 |
申请号 |
CA20052584396 |
申请日期 |
2005.11.04 |
申请人 |
SIRION THERAPEUTICS, INC. |
发明人 |
LICHTER, JAY;WIDDER, KENNETH;MATA, NATHAN L.;HAN, YUN |
分类号 |
A61K38/00;A01N31/04 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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地址 |
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