Process for the preparation of indole derivatives by enzymatic acylation

摘要

A process for the preparation of compounds of formula (1), by enzymatic acylation to form compounds of formulae (3a) and (3a) and then reacting the compound of formula (3a) with a compound introducing the radical of formula -CH₂-COOR₈, R₈ being an organic radical, and then reducing, and optionally hydrolysing, the resulting compound of formula (4).