发明名称 |
ANTI-FC-GAMMA RIIB RECEPTOR ANTIBODY AND USES THEREFOR |
摘要 |
<p>The present application describes antibodies that selectively bind human FcgammaRIIB, with little or no binding to other human FcgammaRs, e.g., human FcgammaRIIA. The invention also provides isolated bispecific antibodies comprising an antibody that selectively binds FcgammaRIIB, and a second antibody that specifically binds an activating receptor. Various uses, including therapeutic uses, for those antibodies are also described, including administration with anti-tumor antibodies and methods of inhibiting immune responses and suppressing histamine release.</p> |
申请公布号 |
WO2006028956(A9) |
申请公布日期 |
2006.05.18 |
申请号 |
WO2005US31281 |
申请日期 |
2005.09.01 |
申请人 |
GENENTECH, INC.;CHAN, ANDREW C.;SHIELDS, ROBERT L.;WU, LAWREN |
发明人 |
CHAN, ANDREW C.;SHIELDS, ROBERT L.;WU, LAWREN |
分类号 |
|
主分类号 |
|
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|