发明名称 |
Irreversibly-inactivated pepsinogen fragment and pharmaceutical compositions comprising this fragment for detecting, preventing, and treating HIV |
摘要 |
The inventions provide an isolated antiviral peptide characterized by the amino acid sequence GDEPLENYLDTEYF (SEQ ID:NO 1) and a significant in vitro binding affinity for HIV-1 gp 120 and gp 41 and human CD4 cells. It has postulated anti-retroviral activity in vivo, particularly anti-HIV-1 activity. The inventions further provide pharmaceutical compositions comprising this peptide and methods for preventing, treating, and diagnosing HIV-1 infections and HIV-1 related conditions such as AIDS and ARC with these compositions.
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申请公布号 |
US2006104992(A1) |
申请公布日期 |
2006.05.18 |
申请号 |
US20050177427 |
申请日期 |
2005.07.11 |
申请人 |
ZHABILOV HARRY H |
发明人 |
ZHABILOV HARRY H. |
分类号 |
A61K39/12;A61K38/00;C07K2/00;C07K4/00;C07K5/00;C07K7/00;C07K14/00;C07K16/00;C07K17/00 |
主分类号 |
A61K39/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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