发明名称 |
SWELLABLE DOSAGE FORM COMPRISING GELLAN GUM |
摘要 |
A novel dosage form. The dosage form is presented in particulate form and before oral ingestion the particulate material is subjected to an aqueous medium, whereby it is converted to a semi-solid form by swelling or gelling of one or more of the components, especially of a gellan gum, of the particulate matter. The invention also relates to a vehicle for oral administration of one or more active substances, the vehicle comprising a gellan gum arranged in a configuration allowing optimal water diffusion so that upon addition of a predetermined amount of an aqueous medium, without the necessity of applying shear forces or other mixing forces, within a time period of 5 minutes or less swells and/or gels and the texture of the swelled vehicle being similar to that of a soft pudding and having a viscosity of at least about 10,000 cps as measured by a Brookfield Viscometer with a #4 LV spindle at 6 rpm and at 20-25°C. In one embodiment of the invention, the particulate matter can be moulded into a desired shape or pressed onto a dispensing unit such as a spoon. |
申请公布号 |
WO2005107713(A3) |
申请公布日期 |
2006.05.18 |
申请号 |
WO2005DK00317 |
申请日期 |
2005.05.11 |
申请人 |
EGALET A/S;BAR-SHALOM, DANIEL;SLOT, LILLIAN;FISCHER, GINA;HEMMINGSEN, PERNILLE, HOEYRUP |
发明人 |
BAR-SHALOM, DANIEL;SLOT, LILLIAN;FISCHER, GINA;HEMMINGSEN, PERNILLE, HOEYRUP |
分类号 |
A61K9/16;A61J7/00;A61K9/00;A61K9/20;A61K31/167;A61K31/192;A61K31/4415;A61K33/26 |
主分类号 |
A61K9/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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