IMPROVED METHOD OF ELECTROCHEMICAL ANALYSIS OF AN ANALYTE

摘要

A method of electrochemical analysis using a sensor electrode specific for an analyte under test. The method comprises immersing the sensor electrode in a sample solution suspected of containing the analyte; forming an electrochemically active complex by exposure to solutions containing secondary receptors or competing molecules labelled with a charged or enzyme label; and subsequently exposing the sensor to an electrochemically active solution. The measurement step comprises driving the sensor electrode potential to a predetermined fixed potential by applying a current or activation waveform then monitoring the potential difference between the sensor electrode and a reference electrode following removal of the holding current. Current, rate and potential can all be measured and used to determine analyte concentration or sensor state.