DUAL ANTIPLATELET/ANTICOAGULANT PYRIDOXINE ANALOGS

摘要

Pyridoxine analogs , particularly bis-amidine pyridoxine analogs with antiplatelet and anticoagulant characteristics for the treatment of cardiovascular, cerebrovascular and cardiovascular related diseases and symptoms are described. The methods are directed to administering pharmaceutical compositions comprising substituted bis-amidine pyridoxine analogs having the following formulas:(I),(II),(III). wherein at least two of substituents R<SUP>1</SUP>- R<SUP>6</SUP> have amidine groups.