发明名称 |
Verwendung von 13C oder 14C-markierten Aminosäuren oder Peptiden als Diagnosemittel für die exokrin Pankreasfunktion |
摘要 |
A diagnostic agent for pancreatic exocrine function comprising an amino acid or a peptide containing at least one <13>C or <14>C atom, or a pharmaceutically acceptable salt thereof other than Bz-Tyr-<13>C-PABA is provided. A <13>C- or <14>C-labeled compound represented by the following formula (II): X2-R2-Y2-Z1 or a salt thereof, wherein X2 is a hydrogen atom or a protecting group, R2 is a peptide of 2 to 5 amino acids, an amino acid or a single bond, Y2 is an amino acid, Z1 is an amino acid optionally having a protecting group, and at least one of the amino acids in R2,Y2and Z1, or at least one of the protecting groups in X2 and Z1 when the protecting groups contain a carbon atom, is <13>C or <14>C-labeled. <IMAGE> |
申请公布号 |
DE69927089(T2) |
申请公布日期 |
2006.05.18 |
申请号 |
DE1999627089T |
申请日期 |
1999.06.04 |
申请人 |
TOKYO GAS CO. LTD., TOKIO/TOKYO |
发明人 |
KOHNO, TADASHI;HOSOI, ISABURO;OHSHIMA, JUNKO;SHIBATA, KUNIHIKO;ITO, ASUKA |
分类号 |
A61K49/00;A61K51/08;A61K49/18;A61K51/12;A61P1/00;A61P3/00;C07K5/062;C07K5/065;C07K5/068;C07K7/06;C07K14/00;G01N33/497 |
主分类号 |
A61K49/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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