| 发明名称 |
Dihydrofoltare reductase inhibition by epigallocatechin gallate compounds |
| 摘要 |
This invention relates to the identification, production and use of Dihydrofolate Reductase (DHFR) inhibitors based on the green tea catechin Epigallocatechin Gallate (EGCG). These inhibitors are, for example, useful in therapy, in particular for the treatment of cancer, infection and inflammatory conditions.
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| 申请公布号 |
WO2006021888(B1) |
申请公布日期 |
2006.05.18 |
| 申请号 |
WO2005IB03009 |
申请日期 |
2005.08.25 |
| 申请人 |
UNIVERSIDAD DE MURCIA;RODRIGUEZ-LOPEZ JOSE NEPTUNO;VAVARRO-PERAN ENCARNACION MARIA;CABEZAS-HERRERA JUAN |
发明人 |
RODRIGUEZ-LOPEY JOSE NEPTUNO;NAVARRO-PERAN ENCARNACION MARIA;CABEZAS-HERRERA JUAN |
| 分类号 |
C12Q1/32;A61K31/00;A61P31/04;A61P35/00;G01N33/50;G06F19/00 |
主分类号 |
C12Q1/32 |
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