发明名称 IMMORTAL HUMAN PROSTATE EPITHELIAL CELL LINES AND CLONES AND THEIR APPLICATIONS IN RESEARCH AND THERAPY OF PROSTATE CANCER
摘要 <p><P>PROBLEM TO BE SOLVED: To provide immortalized, malignant, human, adult prostate epithelial cell lines or cell lines derived therefrom useful in the diagnosis and treatment of prostate cancer. <P>SOLUTION: More particularly, the present invention relates to cloned, immortalized, malignant, human, adult prostate epithelial cell lines characterized as having loss of at least one of heterozygous allele on chromosome 8p and uses of these cell lines for the diagnosis and treatment of cancer. Furthermore, the present invention provides for the characterization of the cell lines through the analysis of specific chromosomal deletions. <P>COPYRIGHT: (C)2006,JPO&NCIPI</p>
申请公布号 JP2006122052(A) 申请公布日期 2006.05.18
申请号 JP20050326161 申请日期 2005.11.10
申请人 USA GOVERNMENT 发明人 TOPALIAN SUZANNE L;LINEHAN W MARSTON;BRIGHT ROBERT K;VOCKE CATHY D
分类号 C12N5/10;C12N15/09;A61K38/00;A61K39/00;A61P35/00;C07K16/18;C12N5/071;C12N5/09;C12Q1/02;G01N33/15;G01N33/50;G01N33/531 主分类号 C12N5/10
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