摘要 |
<p><P>PROBLEM TO BE SOLVED: To provide immortalized, malignant, human, adult prostate epithelial cell lines or cell lines derived therefrom useful in the diagnosis and treatment of prostate cancer. <P>SOLUTION: More particularly, the present invention relates to cloned, immortalized, malignant, human, adult prostate epithelial cell lines characterized as having loss of at least one of heterozygous allele on chromosome 8p and uses of these cell lines for the diagnosis and treatment of cancer. Furthermore, the present invention provides for the characterization of the cell lines through the analysis of specific chromosomal deletions. <P>COPYRIGHT: (C)2006,JPO&NCIPI</p> |