METHODS OF TREATING HEMATOLOGICAL MALIGNANCIES WITH NUCLEOSIDE ANALOG DRUGS
摘要
The present invention provides methods of treating hematological malignancie s, including multi-drug resistant malignancies, with 8-amino-adenosine and variants thereof. Also encompassed by the present invention is a method of predicting the response of a patient diagnosed with a hematological malignan cy to treatment with a nucleoside analog and a method of screening candidate drugs for efficacy in treating hematological malignancies.
申请公布号
CA2596543(A1)
申请公布日期
2006.05.18
申请号
CA20052596543
申请日期
2005.11.14
申请人
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM;NORTHWESTERN UNIVERSITY
发明人
PLATANIAS, LEONIDAS C.;ROSEN, STEVEN T.;GHIAS, KULSOOM;GANDHI, VARSHA;KRETT, NANCY L.;MA, CHUNGUANG