Therapies for seizure disorders using RLIP76

摘要

The present invention is a composition identified as a coding region of ralA binding protein 1, wherein the region neighbors a membrane-associated portion of the ralA binding protein 1 and directly effects transport activity and membrane association of the ralA binding protein 1. The composition is used to identify chemical compounds (e.g., antibodies, si-RNA and small molecules) that recognize ralA binding protein 1. The composition and methods of using the composition identify, via screening of chemical libraries, compounds that bind ralA binding protein 1 and medicines for the treatment of seizure disorders.