| 发明名称 |
MUTANT ENTEROTOXIN EFFECTIVE AS A NON-TOXIC ORAL ADJUVANT |
| 摘要 |
<p>Methods and compositions are provided herein for the use of a novel mutant form of E. coli heat-labile enterotoxin which has lost its toxicity but has retained its immunologic activity. This enterotoxin is used in combination with an unrelated antigen to achieve an increased immune response to said antigen when administered as part of an oral vaccine preparation.</p> |
| 申请公布号 |
EP0777490(B1) |
申请公布日期 |
2006.05.17 |
| 申请号 |
EP19950928662 |
申请日期 |
1995.07.18 |
| 申请人 |
THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND |
发明人 |
CLEMENTS, JOHN D.;DICKINSON, BONNY L. |
| 分类号 |
A61K38/00;C12P21/02;A61K39/00;A61K39/02;A61K39/106;A61K39/108;A61K39/39;A61P31/00;A61P31/04;A61P31/12;A61P31/16;A61P37/00;A61P37/04;C07K14/195;C07K14/245;C12R1/19 |
主分类号 |
A61K38/00 |
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