发明名称 |
HLA-A *01-binding T-cell epitope of WT1 |
摘要 |
<p>The present invention refers to an immunogenic HLA-A*01-binding T-cell epitope of the Wilms' tumour 1 protein (WT1) and its utility as a target in immunotherapy. In more detail, the invention refers to a polypeptide comprising an amino acid sequence as depicted in SEQ ID NO: 1, to an antibody directed to said polypeptide, to a polynucleotide encoding said amino acid sequence and to a polynucleotide which is complementary to said polynucleotide. The invention further refers to pharmaceutical compositions and in vitro applications.</p> |
申请公布号 |
EP1657250(A1) |
申请公布日期 |
2006.05.17 |
申请号 |
EP20040026827 |
申请日期 |
2004.11.11 |
申请人 |
CHARITE - UNIVERSITAETSMEDIZIN BERLIN |
发明人 |
SCHEIBENBOGEN, CARMEN;ASEMISSEN, ANNE MARIE;STEVANOVIC, STEFAN;KEILHOLZ, ULRICH |
分类号 |
C07K14/47;A61K39/00;C07K7/04;C12Q1/68;G01N33/574 |
主分类号 |
C07K14/47 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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