发明名称 HLA-A *01-binding T-cell epitope of WT1
摘要 <p>The present invention refers to an immunogenic HLA-A*01-binding T-cell epitope of the Wilms' tumour 1 protein (WT1) and its utility as a target in immunotherapy. In more detail, the invention refers to a polypeptide comprising an amino acid sequence as depicted in SEQ ID NO: 1, to an antibody directed to said polypeptide, to a polynucleotide encoding said amino acid sequence and to a polynucleotide which is complementary to said polynucleotide. The invention further refers to pharmaceutical compositions and in vitro applications.</p>
申请公布号 EP1657250(A1) 申请公布日期 2006.05.17
申请号 EP20040026827 申请日期 2004.11.11
申请人 CHARITE - UNIVERSITAETSMEDIZIN BERLIN 发明人 SCHEIBENBOGEN, CARMEN;ASEMISSEN, ANNE MARIE;STEVANOVIC, STEFAN;KEILHOLZ, ULRICH
分类号 C07K14/47;A61K39/00;C07K7/04;C12Q1/68;G01N33/574 主分类号 C07K14/47
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