发明名称 |
PYRROLO PYRIMIDINES AS AGENTS FOR THE INHIBITION OF CYSTEIN PROTEASES |
摘要 |
<p>The invention provides compounds of Formula I or a pharmaceutically acceptable salt or ester thereof wherein the symbols have meaning as defined, which are inhibitors of cathepsin K and find use pharmaceutically for treatment of diseases and medical conditions in which cathepsin K is implicated, e.g. various disorders including inflammation, rheumatoid arthritis, osteoarthritis, osteoporosis and tumors.</p> |
申请公布号 |
EP1423391(B1) |
申请公布日期 |
2006.05.17 |
申请号 |
EP20020797553 |
申请日期 |
2002.08.29 |
申请人 |
NOVARTIS AG;NOVARTIS PHARMA GMBH |
发明人 |
BETSCHART, CLAUDIA;HAYAKAWA, KENJI;IRIE, OSAMU;SAKAKI, JUNICHI;IWASAKI, GENJI;LATTMANN, RENE;MISSBACH, MARTIN;TENO, NAOKI |
分类号 |
C07D487/04;A61K31/519;A61K31/52;A61K31/529;A61K31/5377;A61K31/551;A61P9/00;A61P9/10;A61P11/00;A61P19/02;A61P19/10;A61P29/00;A61P31/00;A61P35/00;A61P35/04;A61P37/02;A61P37/06;A61P43/00;C07D473/00;C07D519/00 |
主分类号 |
C07D487/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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