发明名称 Compounds which inhibits protein prenylation ( e.g. geranylgeranyltransferase or farnesyltransferase inhibitors) for treating Parkinson's disease
摘要 The invention relates to compounds and their uses, particularly in the pharmaceutical industry. The invention more specifically relates to new uses of compounds that inhibit the prenylation of proteins, in particular the geranylgeranyl and/or farnesyl modifications of proteins, for treating neurodegeneration involving oxidative stress and, more particularly, Parkinson's disease. The invention also relates to corresponding methods of treatment, and can be used in human subjects for preventive or curative treatment, either alone or in combination with other active agents or treatments.
申请公布号 EP1656931(A1) 申请公布日期 2006.05.17
申请号 EP20040292697 申请日期 2004.11.15
申请人 EXONHIT THERAPEUTICS SA 发明人 SCHWIGHOFFER, FABIEN;DESIRE, LAURENT
分类号 A61K31/00;A61K31/216 主分类号 A61K31/00
代理机构 代理人
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