发明名称 METHOD FOR PRODUCING POLYPEPTIDE VIA BACTERIAL FERMENTATION
摘要 A process for producing a polypeptide of interest from fermentation of bacterial host cells comprising nucleic acid encoding the polypeptide is provided. In this method, the host cells employed have an inactivated election transport chain. Further provided is a method for determining if a particular bacterial cell culture has a propensity for dissolved oxygen instability when fermented on a large scale.
申请公布号 CA2147468(C) 申请公布日期 2006.05.16
申请号 CA19932147468 申请日期 1993.11.19
申请人 GENENTECH, INC. 发明人 SWARTZ, JAMES R.
分类号 C12N15/09;C12P21/00;B01F3/04;B01F15/00;C07K14/65;C12M1/00;C12M1/06;C12M1/36;C12M3/02;C12N1/20;C12N1/21;C12N9/02;C12N15/01;C12P21/02;C12Q1/02 主分类号 C12N15/09
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