发明名称 Non-nucleoside reverse transcriptase inhibitors
摘要 Provided are compounds of the general formula I: wherein R 2 is selected from the group consisting of H, F, Cl, (C 1-4 ) alkyl, (C 3-4 ) cycloalkyl and CF 3 ; R 4 is H or Me; R 5 is H, Me or Et, with the proviso that R 4 and R 5 are not both Me, and if R 4 is Me then R 5 cannot be Et; R 11 is Et, cyclopropyl, propyl, isopropyl, or isobutyl; and Q is selected from the group consisting of: and pharmaceutically acceptable salts thereof, as inhibitors of HIV reverse transcriptase, wild-type and several mutant strains.
申请公布号 EP1655300(A1) 申请公布日期 2006.05.10
申请号 EP20060100695 申请日期 2001.06.14
申请人 BOEHRINGER INGELHEIM (CANADA) LTD. 发明人 SIMONEAU, BRUNO, DR.
分类号 C07D471/14;A61K31/55;C07D221/00;C07D243/00 主分类号 C07D471/14
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