| 摘要 |
N-(Indolylalkyl)-benzofuranyloxyalkylamine derivatives (I) are new. N-(Indolylalkyl)-benzofuranyloxyalkylamine derivatives of formula (I) and their derivatives, solvates and stereoisomers (including mixtures in all proportions) are new. [Image] R 11 or 2 of OH, OA, CN, halo, COR and/or CH 2R; R : OH, OA, NH 2, NHA or NA 2; R 2, R 3H or A; R 4H or 1 or 2 of OH, OA, NH 2, NHA, NA 2, CN, halo, COR and/or CH 2R; A : 1-6C alkyl; m : 2-6, and n : 1-4. An independent claim is included for the preparation of (I). ACTIVITY : Tranquilizer; Antidepressant; Neuroleptic; Hypotensive; Nootropic; Neuroprotective; Vasotropic; Hypnotic; Anorectic; Cerebroprotective; Antiinflammatory; Vulnerary; Antimigraine; Antiaddictive; Gynecological; Osteopathic. MECHANISM OF ACTION : High affinity serotonin receptor (5-hydroxytryptamine (HT)(1A) receptor) agonist; 5-HT(1D) receptor agonist; 5-HT(2A) receptor agonist; 5-HT reuptake inhibitor. |
