发明名称 |
METHOD FOR GENE INTRODUCTION INTO TARGET CELLS BY RETROVIRUS |
摘要 |
<p>A method for increasing the efficiency of gene transfer into target cells with a retrovirus is disclosed. In the method, the target cells are infected with the retrovirus in the presence of either a mixture of an effective amount of a functional material having retrovirus binding domain and an effective amount of another functional material having target cell binding domain, or an effective amount of a functional material having these binding domains on the same molecule. The functional materials may be used without immobilization or with immobilized on beads. The method is useful, for example, gene therapy.</p> |
申请公布号 |
EP0870839(B1) |
申请公布日期 |
2006.05.10 |
申请号 |
EP19960937515 |
申请日期 |
1996.11.07 |
申请人 |
TAKARA BIO INC. |
发明人 |
ASADA, KIYOZO;UEMORI, TAKASHI;UENO, TAKASHI;KOYAMA, NOBUTO;HASHINO, KIMIKAZU;KATO, IKUNOSHIU |
分类号 |
C12N15/86;A61K48/00;C07K14/505;C07K14/78;C12N5/10;C12N9/10;C12N15/12;C12N15/867 |
主分类号 |
C12N15/86 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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