发明名称 |
ORAL PHARMACEUTICAL COMPOSITION FOR SOFT CAPSULES CONTAININGVINORELBINE AND METHOD OF TREATMENT |
摘要 |
The invention described herein relates to a pharmaceutical composition containing vinorelbine as an active ingredient which is suitable for encapsulation in soft capsules. The liquid oral pharmaceutical composition suitable for a liquid fill composition for a soft capsule dosage form comprises: vinorelbine or a pharmaceutically acceptable salt thereof; ethanol; water; glycerol; and polyethylene glycol. In a preferred embodiment, the tartrate salt form of vinorelbine is used in the composition . The invention also provides for a method of treating cancer comprising orally administering, to a patient in need of treatment thereof, a soft capsule comprising the pharmaceutical composition of the invention.
|
申请公布号 |
CA2388431(C) |
申请公布日期 |
2006.05.09 |
申请号 |
CA20022388431 |
申请日期 |
2002.05.31 |
申请人 |
R.P. SCHERER TECHNOLOGIES, INC. |
发明人 |
BOHN, MARIE-MADELEINE;HEINTZ, NORBERT;BOUGARET, JOEL;LEVERD, ELIE |
分类号 |
A61K31/475;A61K31/775;A61P35/00 |
主分类号 |
A61K31/475 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|