| 发明名称 |
A BACTERIAL NITROREDUCTASE GENE-PRODRUG SYSTEM |
| 摘要 |
The system of the invention comprises: (i) a viral vector comprising a nucle otide sequence encoding a nitroreductase, which nitroreductase in capable of converting a prodrug into a cytotoxic drug; and (ii) a prodrug capable of being converted into a cytoto xic drug by the nitroreductase encoded by the vector.
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| 申请公布号 |
CA2175687(C) |
申请公布日期 |
2006.05.09 |
| 申请号 |
CA19942175687 |
申请日期 |
1994.11.04 |
| 申请人 |
CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED |
发明人 |
CONNORS, THOMAS;KNOX, RICHARD;SHERWOOD, ROGER |
| 分类号 |
C12N15/00;C12N15/53;A61K31/265;A61K31/27;A61K31/40;A61K31/70;A61K35/76;A61K38/00;A61K38/44;A61K45/00;A61K47/42;A61K48/00;A61P35/00;A61P43/00;C07H21/04;C07K14/195;C12N9/02;C12N15/86 |
主分类号 |
C12N15/00 |
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