发明名称 |
Labeled protein and its producing method, labeling compound to be used in the method, and method for analyzing function of genes |
摘要 |
A protein having a labeling compound attached to its C-terminal, in which the compound comprises a label portion comprising a label substance and an acceptor portion comprising a compound having an ability of binding to a C-terminal of a synthesized protein when protein synthesis is carried out in a cell-free protein synthesis system or in a living cell is provided. Also, a method for producing the protein comprising the step of performing synthesis of a protein in a cell-free protein synthesis system or in a living cell in the presence of a labeling compound comprising a label portion comprising a label substance and an acceptor portion comprising a compound having an ability of binding to a C-terminal of a synthesized protein when protein synthesis is carried out in the cell-free protein synthesis system or in the living cell, the labeling compound being present at a concentration effective for the labeling compound to bind to the C-terminal of the synthesized protein is provided. Also, the labeling compound and a method for analyzing a function of a gene are further provided.
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申请公布号 |
US7041446(B2) |
申请公布日期 |
2006.05.09 |
申请号 |
US20010794128 |
申请日期 |
2001.02.28 |
申请人 |
MITSUBISHI CHEMICAL CORPORATION |
发明人 |
YANAGAWA HIROSHI;NEMOTO NAOTO;MIYAMOTO ETSUKO |
分类号 |
C07H19/207;C12Q1/68;C07H19/04;C07H19/20;C07H21/02;C07H21/04;C07K1/13;C07K14/00 |
主分类号 |
C07H19/207 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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