发明名称 |
Fluorinated phenyl thiophenyl derivatives and their use for imaging serotonin transporters |
摘要 |
This invention relates to novel fluorinated phenyl thiphenyl (also named diarylsulfide) derivatives and their use in Positron Emission Tomagraphy (PET) imaging of Serotonin Transporters (SERTS). The present invention also provides diagnostic compositions comprising the novel compounds of the present invention, and a pharmaceutically acceptable carrier or diluent. The invention further provides a method of imaging SERTS, comprising introducing into a patient a detectable quantity of a labeled compound of the present invetion, or a pharmaceutically acceptable salt, ester, amide or prodrug thereof.
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申请公布号 |
US7041851(B2) |
申请公布日期 |
2006.05.09 |
申请号 |
US20030388363 |
申请日期 |
2003.03.14 |
申请人 |
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA |
发明人 |
KUNG HANK F.;SHIUE CHYNG-YANN;OYA SHUNICHI;CHOI SEOK RYE;SHIUE GRACE G.;FANG PING |
分类号 |
C07C321/28;A61K31/10;A61K51/04;C07C321/30;C07C323/32;C07C323/37 |
主分类号 |
C07C321/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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