| 发明名称 |
Multicyclic compounds and their use as inhibitors of parp, begfr2 and mlk3 enzymes |
| 摘要 |
The present invention is directed to novel multicyclic molecules of formula Ia that mediate enzymatic activity. In particular, the compounds may be effective in the treatment of diseases or disease states related to the activity of PARP, VEGFR2, and MLK3 enzymes, including, for example, neurodegenerative diseases, inflammation, ischemia, and cancer. |
| 申请公布号 |
HK1051369(A1) |
申请公布日期 |
2006.05.04 |
| 申请号 |
HK20030103639 |
申请日期 |
2003.05.22 |
| 申请人 |
CEPHALON, INC. |
发明人 |
ATOR, MARK, A.;RON BIHOVSKY;SANKAR CHATTERJEE;DEREK DUNN;HUDKINS, ROBERT, L. |
| 分类号 |
A61K31/407;A61K31/41;A61K31/4178;A61K31/4196;A61K31/427;A61K31/4412;A61K31/4439;A61K31/4453;A61K31/497;A61K31/501;A61K31/5377;A61P3/10;A61P9/10;A61P15/00;A61P17/06;A61P25/14;A61P25/16;A61P25/28;A61P27/02;A61P29/00;A61P35/00;A61P43/00;C07D;C07D471/14;C07D487/04;C07D491/04;C07D491/14;C07D495/04;C07D519/00;(IPC1-7):C07D;A61K;A61P |
主分类号 |
A61K31/407 |
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