发明名称 Tetralin histamine-3 receptor antagonists
摘要 This invention is directed to compounds of the formula I as defined herein, or a pharmaceutically acceptable salt thereof; a pharmaceutical composition containing a compound of formula I, a method of treatment of a disorder or condition that may be treated by antagonizing histamine H3 receptors, the method comprising administering to a mammal in need of such treatment a compound of formula I as described above, and a method of treatment of a disorder or condition selected from the group consisting of depression, mood disorders, schizophrenia, anxiety disorders, Alzheimer's disease, attention-deficit disorder (ADD), attention-deficit hyperactivity disorder (ADHD), psychotic disorders, sleep disorders, obesity, dizziness, epilepsy, motion sickness, respiratory diseases, allergy, allergy-induced airway responses, allergic rhinitis, nasal congestion, allergic congestion, congestion, hypotension, cardiovascular disease, diseases of the GI tract, hyper and hypo motility and acidic secretion of the gastro-intestinal tract, the method comprising administering to a mammal in need of such treatment a compound of formula I as described above.
申请公布号 US2006094719(A1) 申请公布日期 2006.05.04
申请号 US20050256339 申请日期 2005.10.21
申请人 PFIZER INC 发明人 HOWARD HARRY R.JR.;ELLIOTT MARK L.
分类号 A61K31/5377;A61K31/454;A61K31/496;C07D401/02;C07D403/02;C07D413/02 主分类号 A61K31/5377
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