发明名称 |
Selective process for producing an anomer of a 1-phosphorylated saccharide derivative and process for producing a nucleoside |
摘要 |
A desired isomer is selectively prepared by phosphorolyzing and isomerizing an anomer mixture of a 1-phosphorylated saccharide derivative while crystallizing one of the isomers to displace the equilibrium. Furthermore, using the action of a nucleoside phosphorylase, a nucleoside is prepared from the 1-phosphorylated saccharide derivative obtained and a base with improved stereoselectivity and a higher yield. This process is an anomer-selective process for preparing a 1-phosphorylated saccharide derivative and a nucleoside.
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申请公布号 |
US2006094869(A1) |
申请公布日期 |
2006.05.04 |
申请号 |
US20050287212 |
申请日期 |
2005.11.28 |
申请人 |
MITSUI CHEMICALS, INC. |
发明人 |
KOMATSU HIRONORI;AWANO HIROKAZU;FUKAZAWA NOBUYUKI;ITO KIYOSHI;IKEDA ICHIROU;ARAKI TADASHI;NAKAMURA TAKESHI;ASANO TAMOTSU;FUJIWARA JUNYA;ANDO TOMOYUKI;TSUCHIYA KATSUTOSHI;MARUYAMA KYOKO;UMETANI HIDEKI;YAMAUCHI TAKAHIRO;MIYAKE HITOKI |
分类号 |
C07H19/04;C07H19/00;C07H19/10;C07H19/20 |
主分类号 |
C07H19/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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