Particles for use in diagnosis and therapy, especially for binding therapeutic agent for treating e.g. tumors and bacterial, rheumatic, neurologic and thrombotic diseases, have nanocrystalline magnetic core and envelope enclosing core

摘要

Particles (I) for use in diagnosis and therapy, especially for binding with an active therapeutic agent, have a nanocrystalline magnetic core and an envelope enclosing the core. The core comprises at least 95 wt.% iron oxide and the specific saturation magnetization of the particle is at least 110 Am 2>/kg iron. Independent claims are also included for the following: (A) medicament or diagnostic agent containing (I); (B) preparation of magnetic particles for use in diagosis and therapy, particularly (I); (C) use of (I) for the manufacture of a medicament or in diagnosis, where (I) are bound to an active agent or a diagnostic agent, respectively. ACTIVITY : Cytostatic; Antibacterial; Antirheumatic; Anticonvulsant; Gynecological; Osteopathic; Vasotropic; Thrombolytic; Neuroprotective; Auditory; MECHANISM OF ACTION : None given.