摘要 |
The invention relates to new therapeutically useful pyridazin-3(2H)-one derivatives of Formula (I) and to pharmaceutical compositions containing them. These compounds are potent and selective inhibitors of phosphodiesterase 4 (PDE4) and are thus useful in the treatment, prevention or suppression of pathological conditions, diseases and disorders known to be susceptible of being improved by inhibition of PDE4 such as asthma, chronic obstructive pulmonary disease, rheumatoid arthritis, atopic dermatitis, psoriasis or irritable bowel disease.
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申请人 |
ALMIRALL PRODESFARMA, SA;BUIL ALBERO, MARIA ANTONIA;DAL PIAZ, VITTORIO;GARRIDO RUBIO, YOLANDA;GRACIA FERRER, JORDI;PAGES SANTACANA, LLUIS MIQUEL;TALTAVULL MOLL, JOAN |
发明人 |
BUIL ALBERO, MARIA ANTONIA;DAL PIAZ, VITTORIO;GARRIDO RUBIO, YOLANDA;GRACIA FERRER, JORDI;PAGES SANTACANA, LLUIS MIQUEL;TALTAVULL MOLL, JOAN |