| 摘要 |
A prostaglandin derivative represented by Formula (I): wherein X is a halogen atom in the alpha- or beta-substitution, Y is an ethylene group, a vinylene group or an ethynylene group, R<SUP>1 </SUP>is a C<SUB>3-10 </SUB>cycloalkyl group, a C<SUB>3-10 </SUB>cycloalkyl group substituted with a C<SUB>1-4 </SUB>straight or branched chain alkyl group or a C<SUB>4-13 </SUB>cycloalkylalkyl group, R<SUP>2 </SUP>is a hydrogen atom or a CO<SUB>2</SUB>R<SUP>3 </SUP>group (R<SUP>3 </SUP>is a hydrogen atom, a C<SUB>1-4 </SUB>straight or branched chain alkyl group or a C<SUB>2-4 </SUB>straight or branched chain alkenyl group), n is an integer of 1 to 4 and p is 0, 1 or 2, a pharmaceutically acceptable salt thereof or a hydrate thereof.
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