发明名称 |
THIO-SUBSTITUTED PHENBUTAZONE COMPOUNDS AS ANTI-INFLAMMATORY, ANTI-VIRAL AND IMMUNOMODULATORY AGENTS |
摘要 |
<p>The present invention relates to optionally substituted compounds of the formula I or a salts thereof; wherein R<SUB>1 </SUB>is O or S, R<SUB>2 </SUB>is hydrogen or a C<SUB>1</SUB>-C<SUB>10 </SUB>organic group attached by a carbon atom, X is H, O, OO, S or SS R<SUB>3 </SUB>is absent where X=H, is hydrogen or is a hydroxyl or thiol protecting group, R<SUB>4 </SUB>is a hetero- or homo-cyclic aryl group, optionally substituted with a further group R<SUB>5</SUB>, one Y group is S and the other is either H (in which case only one R<SUB>6 </SUB>group is present) or S; and R<SUB>6 </SUB>is, independently, an organic group of molecular weight up to around 500 amu. The invention also provides compositions comprising such compounds and methods of treatment comprising administration of such compositions.</p> |
申请公布号 |
EP1651212(A1) |
申请公布日期 |
2006.05.03 |
申请号 |
EP20040743541 |
申请日期 |
2004.07.23 |
申请人 |
A-VIRAL ASA |
发明人 |
DEKKERS, DAVID, WALTERUS, CORNELIS;AARDEN, LUCIEN, ADRIANUS;TEN BRINKE, JANNA, ALBERDINA |
分类号 |
A61P29/00;A61P31/00;A61P37/00;C07D231/32;(IPC1-7):A61K31/415 |
主分类号 |
A61P29/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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