发明名称 |
ENGINEERED PROTEASES FOR AFFINITY PURIFICATION AND PROCESSING OF FUSION PROTEINS |
摘要 |
<p>The present invention is directed to the identification of a protease prodomain that is capable of binding a corresponding protease with high affinity. The protease prodomain of the present invention is fused to a second protein to form a protease prodomain fusion protein. The presence of a protease prodomain protein in a fusion protein allows for easy and selective purification of the second protein by incubation with the corresponding protease.</p> |
申请公布号 |
EP1651751(A2) |
申请公布日期 |
2006.05.03 |
申请号 |
EP20040777325 |
申请日期 |
2004.06.29 |
申请人 |
UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTE |
发明人 |
BRYAN, PHILIP, N. |
分类号 |
C12N15/52;C12N;C12N9/50;C12N9/54;C12N15/62;C12Q1/37;G01N33/573;(IPC1-7):C12N1/00 |
主分类号 |
C12N15/52 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|