发明名称 |
Method for sequential support-bound synthesis of conjugated oligomeric compounds |
摘要 |
A sequential support-bound synthesis method is disclosed for preparing a conjugated oligomeric compound, preferably a PNA-peptide conjugate or an oligonucleotide-peptide conjugate, using a bridging molecule having at least two N-protecting amino groups. A conjugated oligomeric compound for therapeutic or prophylactic delivery is also disclosed.
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申请公布号 |
US7038037(B2) |
申请公布日期 |
2006.05.02 |
申请号 |
US20020176419 |
申请日期 |
2002.06.20 |
申请人 |
ISIS PHARMACEUTICALS, INC. |
发明人 |
MAIER MARTIN A.;GUZAEV ANDREI P.;MANOHARAN MUTHIAH |
分类号 |
C07H21/00;A61K47/48;C07H21/02;C07H21/04;C07K1/00;C07K7/06;C07K7/08 |
主分类号 |
C07H21/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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