发明名称 Methods and compositions for identifying ligands for nuclear receptors
摘要 A yeast-based system and methods of use therefore are provided for identifying new molecules which activate nuclear receptors in a ligand-dependent fashion. In a preferred embodiment, a method is provided utilizing ecdysone receptor, USP and GRIP I encoding expression vectors which may be used to advantage for screening new and useful insecticidal compounds, detecting insecticidal residues as well as to regulate expression of a gene of interest in a host in a ligand-dependent manner.
申请公布号 US7037656(B2) 申请公布日期 2006.05.02
申请号 US20020204169 申请日期 2002.12.02
申请人 LIFESENSORS, INC. 发明人 TRAN HIEP TUAN;SHAABAN SALAM;ASKARI HOSSEIN;SCHWARTZ MICHAEL;BUTT TAUSEEF
分类号 C12Q1/68;A61K31/00;C12N15/10 主分类号 C12Q1/68
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