发明名称 Derivatives of piperidinyl-and piperazinyl-alkyl carbamates, preparation methods thereof and application of same in therapeutics
摘要 Compound corresponding to the general formula (I): in which A=N or CR<SUB>2</SUB>; R<SUB>2</SUB>-H, F, OH, CN, CF<SUB>3</SUB>, C<SUB>1-6</SUB>-alkyl, C<SUB>12-6</SUB>-alkoxy; n=2 or 3 and m=2 when A=N; n=1, 2 or 3 and m=1 or 2 when A=CR<SUB>2</SUB>; B=covalent bond or C<SUB>1-8</SUB>-alkylene; R<SUB>1</SUB>=optionally substituted heteroaryl; R<SUB>3</SUB>-CHR<SUB>4</SUB>CONHR<SUB>5</SUB>; R<SUB>4</SUB>-H or C<SUB>1-6</SUB>-alkyl; R<SUB>5</SUB>-H, C<SUB>1-6</SUB>-alkyl, C<SUB>3-7</SUB>-cycloalkyl, C<SUB>3-7</SUB>-cycloalkyl-C<SUB>1</SUB>-C<SUB>6</SUB>-alkylene; in the form of a base, an acid-addition salt, a hydrate or a solvate. Therapeutic uses thereof
申请公布号 US2006089344(A1) 申请公布日期 2006.04.27
申请号 US20050262211 申请日期 2005.10.28
申请人 SANOFI-AVENTIS 发明人 ABOUABDELLAH AHMED;BURNIER PHILIPPE;HOORNAERT CHRISTIAN;JEUNESSE JEAN;PUECH FREDERIC
分类号 A61K31/519;A61K31/435;A61K31/436;A61K31/44;A61K31/495;A61K31/496;A61K31/506;A61K31/517;A61P9/00;A61P25/00;A61P31/00;A61P35/00;A61P37/00;C07D211/26;C07D213/38;C07D295/12;C07D295/13;C07D401/04;C07D401/14;C07D403/14;C07D413/04;C07D413/14;C07D417/04;C07D417/14;C07D471/04;C07D491/04;C07D491/048;C07D495/04 主分类号 A61K31/519
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