| 摘要 |
<p>Oximes of formula (I) have anti-inflammatory and analgesic activity (where R1 = H or CH3; R2 and R3 = H, OCH3, OC2H5 or Cl; R4 and R5 = CH3, C2H5, or together with the N atom, form a pyridine, piperidine 4-methyl piperidine, piperazine, azine, pyrrole, pyrrolidine, morpholine or thiomorpholine ring. n >=1). The cpds. are prepd. by reaction of a p-OH benzaldehyde or a p-OH benzaldehyde or a p-OH acetophenone with an omega-chloro alkanoic acid, followed by conversion to the amide and reaction with hydroxylamine hydrochloride.</p> |
