发明名称 |
SYSTEM AND METHOD OF DETERMINING PROTEOMIC DIFFERENCES |
摘要 |
The present invention relates to a system and methods for identifying differential peptide expression in one or more peptide populations. Each population is labeled with a discernable label and provides a mechanism to resolve mixed peptide populations using mass spectroscopy-based techniques. Spectra produced by the peptide sample are used to interrogate a spectral database in which peptide sequences of known spectra are stored. In addition to providing sequence information, the methods presented herein may be used to determine qualitative and quantitative measurements of peptide expression. These measurements may further be used to determine proteomic differences and novel peptide expression. |
申请公布号 |
EP1428019(A4) |
申请公布日期 |
2006.04.26 |
申请号 |
EP20020759149 |
申请日期 |
2002.07.12 |
申请人 |
SYNGENTA PARTICIPATIONS AG |
发明人 |
WASHBURN, MICHAEL;DECIU, COSMIN;ULASEK, RYAN |
分类号 |
G01N30/02;G01N30/72;G01N33/58;G01N33/68;G06F19/18 |
主分类号 |
G01N30/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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