发明名称 Methods and compositions for improving recombinant protein production
摘要 Nucleic acid molecules modified to enhance recombinant protein, e.g., antibody, expression and/or reduce or eliminate mis-spliced and/or intron read-through (IRT) by-products are disclosed. The invention also provides methods for producing proteins devoid of mis-spliced and/or intron read-through by-products by the use of such vectors in host cells under cell culture conditions suitable for recombinant protein expression.
申请公布号 AU2005294131(A1) 申请公布日期 2006.04.20
申请号 AU20050294131 申请日期 2005.10.05
申请人 WYETH 发明人 JASON ROUSE;MARTIN S. SINACORE;HALEY A. LAKEN;MARK LEONARD
分类号 A61K39/395;C07K16/00;C12N5/10;C12N15/09;C12N15/13;C12N15/67;C12Q1/68 主分类号 A61K39/395
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